Feline Calicivirus VP2 Is Essential for the Production of Infectious Virions

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Feline calicivirus VP2 is essential for the production of infectious virions.

The third open reading frame (ORF3) located at the 3' end of the genomic RNA of feline calicivirus (FCV) encodes a small (12.2-kDa) minor structural protein of 106 amino acids designated VP2. Point mutations and deletions were introduced into an infectious FCV cDNA clone in order to evaluate the functional importance of ORF3 and its encoded protein, VP2. Deletion of the entire ORF3 sequence was...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2005

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.79.7.4012-4024.2005